Players are able to gain trophies while playing the game. To access your achievements list you have to be in your home. There you are able to click on the trophies menu to access the achievements.
Some trophies require you to have access to restricted content. This content is available if you bought the (DC) Director's cut DLC. This unlocks all content and gives you access to all restricted content including new areas on the Fourth Island.
| Trophy | Description | Guide | DC |
|---|---|---|---|
| Maxed Baby! | Master a Profession | No | |
| Rhodes Scholar | Get 999 Intelligence | No | |
| Gym Rat | Get 999 Strength | No | |
| Vigilante Justice | Eliminate all Mobsters, Gangsters, and miscellania. | No | |
| Power Overwhelming | 999 STR, INT, and CHA | No | |
| Mother Theresa | Get +999 Karma | No | |
| Golden Glove Champ | Win 5 boxing matches | No | |
| Satan Incarnate | -999 Karma | Spam-buy fake IDs, or for non-inventory spammers, *Devil's Food Cake. | No |
| Used Car Salesman | Get 999 Charm | No | |
| Workaholic | Master 15 professions | Professions | No |
| Charlie Sheen | Eat, Drink, or Smoke to needing medical attention | No | |
| Maximus Prime | All stats to 2,000 | No | |
| Game Over Man | Get married | Marriage | No |
| Five Million Dollar Man | Have $5,000,000 on hand | No | |
| 10 Million Dollar Man | Have $10,000,000 on hand | No | |
| Great Scott! | Get the Hoverboard | Trophemons | No |
| Career Criminal | Go to Jail 5 Times | Occasional upon aftermath of Fights, and *Evil jobs. | No |
| Penthouse Living | Buy the Penthouse Key | No | |
| Monopoly | Buy every available business | No | |
| Armed to the Teeth | All weapons owned | The Rank 3 Sledgehammer and Flamethrower is *what matters to the achievement. | No |
| Hustler | Win $50,000 gambling | ||
| "To the Lab!" | Own the Lab Key | Main Quest | No |
| Castle Crasher | Win a Castle | Castle | Yes |
| E.T Go Home | Help the alien get home | The Alien | Yes |
| Pwnerer's Clearing House | Clear all combat zones 5 times | No | |
| Speed Run | Get the Lab Key within 15 Days | No | |
| Fast Cash | Earn $100,000 in the first 10 days | No | |
| Caged Animal | Win 10 cage fights. | No | |
| Hail to the King, Baby | Master Politician | Yes | |
| Hef | Buy the Mansion key | Yes |